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Volume 7, Number 5—October 2001
Dispatch

Fluoroquinolone Resistance among Streptococcus pneumoniae in Hong Kong Linked to the Spanish 23F Clone

Pak Leung Ho*, Wing Cheong Yam*, Terence K.M. Cheung*, Wilson W.S. Ng*, Tak Lun Que†, Dominic N.C. Tsang‡, Tak Keung Ng§, and Wing Hong Seto*
Author affiliations: *University of Hong Kong, Hong Kong Special Administrative Region (SAR), China; †Tuen Mun Hospital, Hong Kong SAR, China; ‡Queen Elizabeth Hospital, Hong Kong SAR, China; §Princess Margaret Hospital, Hong Kong SAR, China

Main Article

Table

Distribution of capsular types in 140 strains of mucosal Streptococcus pneumoniae with respect to age and resistance to ciprofloxacin

Age group (years)
Ciprofloxacin MIC >4 µg/mL
Type <2 2-5 18-49 50-64 65 Noa (n=125)
No. (%) Yes (n=15)
No. (%) No. (%)
19F 4 3 1 4 14 19 (15.2) 7 (46.7) 26 (18.6)
23F 4 12 8 4 30 51 (40.8) 7 (46.7) 58 (41.4)
6A 1 1 3 4 (0.8) 1 (6.7) 5 (3.6)

aNumber of strains for other serotype or serogroup by age groups: <2 years (1 for 6B and 1 untypeable), 2 to 5 years (5 for 6B, 1 for 9V, and 1 untypeable), 18 to 49 years (1 for 10B and 1 for 35), 50 to 64 years (1 for 6B, 1 for 19C, and 1 for 34), and >65 years (6 for 6B, 1 for 7F, 1 for 9A/L, 1 for 10C/F, 1 for 11A, 3 for 13, 1 for 15B, 1 for 19B, 1 for 21, 1 for 22A, 5 for 35, and 15 untypeable). No isolates were obtained from the children in the 6- to 17-year age group. All strains with serotypes or serogroups other than 6A, 19F, and 23F were sensitive to ciprofloxacin.

Main Article

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