Volume 7, Number 7—June 2001
THEME ISSUE
International Conference on Emerging Infectious Diseases 2000
Conference Presentations
Epidemiology, Evolution, and Future of the HIV/AIDS Pandemic
Table 2
Mode of inheritance |
|||
---|---|---|---|
Initial frequency | No dominance | Dominant | Recessive |
0.01 | 1,838 | 1,054 | 41,038 |
0.001 | 2,763 | 1,964 | 401,963 |
0.0001 | 3,684 | 2,884 | 4,002,884 |
aWe are assuming that favored genotype has a 10% advantage over the other genotypes; in the no dominance case, the relative fitness of the heterozygote is intermediate between that of the two homozygotes. With a 1% selective advantage, it would take 10 times as long for the gene to reach a frequency of 50%.
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