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Volume 8, Number 11—November 2002

Dispatch

Genomewide Pattern of Synonymous Nucleotide Substitution in Two Complete Genomes of Mycobacterium tuberculosis

Austin L. Hughes*Comments to Author , Robert Friedman*, and Megan Murray†
Author affiliations: *University of South Carolina, Columbia, South Carolina, USA; †Harvard School of Public Health, Boston, Massachusetts, USA;

Main Article

Figure

A plot of p(A|pS), the probability of assignment of a locus to group A given the observed pS value, as a function of pS at 3,309 loci compared between the H37Rv and CDC1551 genotypes of Mycobacterium tuberculosis. The plot shows the bimodal nature of the distribution of pS values, with overall higher values of pS at the 11 loci having p(A|pS) >50%.

Figure. A plot of p(A|pS), the probability of assignment of a locus to group A given the observed pS value, as a function of pS at 3,309 loci compared between the H37Rv and CDC1551 genotypes of Mycobacterium tuberculosis. The plot shows the bimodal nature of the distribution of pS values, with overall higher values of pS at the 11 loci having p(A|pS) >50%.

Main Article

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