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Volume 8, Number 11—November 2002
THEME ISSUE
Tuberculosis Genotyping

Tuberculosis Genotyping Network, United States

National Tuberculosis Genotyping and Surveillance Network: Analysis of the Genotype Database

Lauren S. Cowan* and Jack T. Crawford*Comments to Author 
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA;

Main Article

Table 3

Distribution of isolates in genotype familiesa

No. isolates/site
No. patterns No. isolates AR CA MA MD MI NJ TX Clustered isolates
(%) Average no. copies of IS6110/isolate (range)
FP sets
W-Beijing 497 946 22 279 88 49 162 144 202 56 19.9 (17–27)
Set A 141 190 37 18 14 19 43 29 30 39 13.1 (10–15)
Set B 97 162 14 33 20 4 15 33 43 52 11.0 (7–15)
Set C 251 414 4 295 9 15 20 53 18 52 11.9 (8–15)
Set D 181 275 11 37 44 32 27 102 22 48 8.9 (6–13)
Set E 119 137 0 37 5 16 16 56 7 20 12.9 (9–15)
Set F 177 321 24 44 31 47 47 71 57 55 9.4 (6–14)
FP 17 54 411 31 59 31 64 65 72 89 70 4.5 (3–6)
Spoligotype family
EA-I 161 558 7 247 71 46 62 51 74 56 1.8 (1–6)
X 113 1,291 61 267 73 98 232 270 290 83 3.1 (1–6)
Haarlem 11 47 1 1 5 23 2 5 10 45 4.9 (1–6)
LAM-1 5 6 0 1 2 2 0 1 0 33 3.7 (1–6)
LAM-2 4 54 0 0 0 51 0 2 1 81 2.6 (1–6)
bovis 19 32 2 8 1 2 5 8 6 41 1.4 (1–5)
africanum 10 19 0 1 1 11 2 3 1 47 4.4 (3–6)

a FP, fingerprint, AR, Arkansas, CA, California; MA, Massachusetts; MD, Maryland; MI, Michigan; NJ, New Jersey, TX, Texas; EA-I, East African-India; LAM, Latin American-Mediterranean.

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