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Volume 8, Number 11—November 2002
THEME ISSUE
Tuberculosis Genotyping

Tuberculosis Genotyping Network, United States

Identifying the Sources of Tuberculosis in Young Children: A Multistate Investigation

Sumi J. Sun*Comments to Author , Diane E. Bennett†, Jennifer Flood*, Ann M. Loeffler*, Steve Kammerer†, and Barbara A. Ellis†
Author affiliations: *California Department of Health Services, Berkeley, California, USA; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA;

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Table 4

Characteristics of refuted and confirmed patients pairsa

Refuted patient pairs
n=8 (%) Confirmed patient pairs
n=44 (%)
Characteristics of young children
Mean age, monthsb 16 13
Female 4 (50) 23 (52)
Race/ethnicity
Black, non-Hispanic 5 (63) 20 (45)
Hispanic 3 (38) 16 (36)
Asian 0 (0) 5 (11)
White, non-Hispanic 0 (0) 1 (2)
Native American/Alaskan Native 0 (0) 2 (5)
Foreign-born 1 (13) 0 (0)
Source patient characteristics
Mean age, yrs 25 31
Female 6 (75) 18 (41)
Race or ethnicity
Black, non-Hispanic 5 (63) 20 (45)
Hispanic 3 (38) 17 (39)
Asian 0 (0) 5 (11)
Native American or Alaskan Native 0 (0) 2 (5)
Foreign-born 3 (38) 20 (45)
Case patient characteristics
Shared household 5 (63) 32 (73)
Discordant drug susceptibilitiesc 0 (0) 3 (7)
Different race/ethnicity 0 (0) 1 (2)

aFor tuberculosis patients <5 years of age and their suspected source patients. Refuted patient pairs are suspected patient pairs with discordant genotypes; confirmed patient pairs are suspected patient pairs with concordant genotypes.
bWilcoxon rank-sum test: p=0.03.
cExcludes two patient pairs in which the children had drug-resistant Mycobacterium tuberculosis strains (streptomycin and ethambutol resistance, respectively), but susceptibility results were not done for the identified source patient.

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