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Volume 8, Number 12—December 2002

Research

Efficacy of Killed Virus Vaccine, Live Attenuated Chimeric Virus Vaccine, and Passive Immunization for Prevention of West Nile virus Encephalitis in Hamster Model

Robert B. Tesh*Comments to Author , Juan Arroyo†, Amelia P.A. Travassos da Rosa*, Hilda Guzman*, Shu-Yuan Xiao*, and Thomas P. Monath†
Author affiliations: *University of Texas Medical Branch, Galveston, Texas, USA; †Acambis, Inc., Cambridge, Massachusetts, USA;

Main Article

Table 6

WNV hemagglutination inhibition antibody titers in adult hamsters 24 h after inoculation (passive immunization) with WNV immune serum, and 7 days later after challenge with WNV (104.0 TCID50 given intraperitoneally)a

Hamster no. 24 h after passive immunization 7 days after challenge with WNV
Group A – received 0.5 mL
WNV immune serum
H-8126 1:40b 0
H-8127 1:20 0
H-8128 1:20 0
H-8129 1:20 0
H-8130 1:20 0
H-8138 1:40 0
H-8139 1:40 1:10
Group B – received 0.1 mL 
WNV immune serum)
H-8131 0 0
H-8132 0 0
H-8133 0 0
H-8134 0 0
H-8135 0 0
H-8136 0 0
H-8137 0 0

aWNV, West Nile virus.
bHemagglutination inhibition antibody titer. 0 = <1:10.

Main Article

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