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Volume 8, Number 2—February 2002

Research

Community-Acquired Klebsiella pneumoniae Bacteremia: Global Differences in Clinical Patterns

Wen-Chien Ko*, David L. Paterson†‡, Anthanasia J. Sagnimeni‡, Dennis S. Hansen§, Anne von Gottberg¶, Sunita Mohapatra#, Jose Maria Casellas**, Herman Goossens††, Lutfiye Mulazimoglu‡‡, Gordon Trenholme#, Keith P. Klugman¶, Joseph G. McCormack‡, and Victor L. Yu†Comments to Author 
Author affiliations: *National Cheng Kung University Medical College, Taiwan; †Veterans Administration Medical Center and University of Pittsburgh, Pittsburgh, Pennsylvania, USA; ‡University of Queensland, Mater Adults Hospital, Brisbane, Australia; §Statens Serum Institut, Copenhagen, Denmark; ¶South African Institute of Medical Research, Johannesburg, South Africa; #Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois, USA; **Sanatorio San Lucas, Buenos Aires, Argentina; ††University Hospital, Antwerp, Belgium; ‡‡Marmara University, Istanbul, Turkey;

Main Article

Table 1

Clinical characteristics of patients with community-acquired Klebsiella pneumoniae bacteremia from Taiwan, South Africa, and other countries

Clinical characteristics Taiwan
(n=96) South Africa
(n=40) Other countries
(n=66) p valuea
Age (mean, years) 58.8 47.2 59.9 0.014
Female, n (%) 35 (38%) 17 (42%) 24 (36%) NS
Underlying diseases, n (%)
Diabetes mellitus 38 (40%) 8 (20%) 19 (29%) 0.06
Liver disease 33 (34%) 6 (15%) 12 (18%) 0.02
Alcoholism 12 (12%) 3 (8%) 1 (2%) 0.08
Malignancy 15 (16%) 3 (8%) 25 (38%) 0.0002
HIV infection 0 (0%) 7 (18%) 0 (0%) 0.0001
Chronic renal failure 6 (6%) 2 (5%) 6 (9%) NS
Organ transplant 0 (0%) 0 (0%) 7 (11%) 0.0006
Corticosteroid use 5 (5%) 1 (3%) 7 (11%) NS
No underlying disease 22 (23%) 21 (52%) 24 (36%) 0.003
Critically illb 30 (31%) 12 (30%) 2 (3%) 0
Death rate at 14 days, n (%) 30 (31%) 24 (60%) 8 (12%) 0

ap values refer to differences between the three regions; NS = not significant at p >0.20.

bCritically ill defined as Pitt bacteremia score >4.

Main Article

1United States: Pittsburgh Veterans Affairs Medical Center, Pittsburgh, Pennsylvania, and Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois; Taiwan: National Cheng Kung University Medical College, Tainan; Australia: Royal Brisbane Hospital, Mater Adults Hospital, and Greenslopes Private Hospital, all in Brisbane; South Africa: Hillbrow Hospital and Baragwanath Hospital, both in Johannesburg; Turkey: Marmara University Hospital, Istanbul; Belgium: University Hospital, Antwerp; and Argentina: San Lucas Hospital and Comunidad Olivos Hospital, both in Buenos Aires.

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