Volume 8, Number 2—February 2002
Community-Acquired Klebsiella pneumoniae Bacteremia: Global Differences in Clinical Patterns
|Characteristic||Bacteremic pneumonia (n=57)||Bacteremia without pneumonia (n=145)||p valuea|
|Resides in South Africa||25 (44%)||15 (10%)||<0.001|
|Serum creatinineb (mg/dL)||2.1||2.3||0.2|
|Blood urea nitrogenb (mg/dL)||34.8||37.9||NS|
|Liver function testsb,c|
|Serum albumin (g/mL)||2.8||3.1||0.05|
|Serum bilirubin (mg/dL)||2.8||2.9||NS|
|Diabetes mellitus (%)||12 (21%)||53 (37%)||0.03|
|Alcoholism (%)||10 (18%)||6 (4%)||0.007|
|Malignancy (%)||7 (12%)||36 (25%)||0.05|
|HIV infection (%)||6 (10%)||1 (1%)||0.002|
|No underlying disease||23 (40%)||44 (30%)||NS (0.17)|
|Critically ill||21 (37%)||23 (16%)||0.001|
|Death rate at 14 days (%)||31 (54%)||32 (22%)||0.0001|
aNS = not significant at p >0.20; AST = aspartate aminotransferase; ALT = alanine aminotransferase.
bLaboratory values are those taken on first visit to a health-care provider; for continuous variables, the figures in the table are mean values.
cBacteremic patients with liver cirrhosis, acute cholangitis, and liver abscess were excluded from the analysis of liver function tests.
1United States: Pittsburgh Veterans Affairs Medical Center, Pittsburgh, Pennsylvania, and Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois; Taiwan: National Cheng Kung University Medical College, Tainan; Australia: Royal Brisbane Hospital, Mater Adults Hospital, and Greenslopes Private Hospital, all in Brisbane; South Africa: Hillbrow Hospital and Baragwanath Hospital, both in Johannesburg; Turkey: Marmara University Hospital, Istanbul; Belgium: University Hospital, Antwerp; and Argentina: San Lucas Hospital and Comunidad Olivos Hospital, both in Buenos Aires.
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