Volume 8, Number 3—March 2002
Research
Listeria monocytogenes Infection in Israel and Review of Cases Worldwide
Yardena Siegman-Igra*
, Rotem Levin*, Miriam Weinberger†, Yoav Golan*, David Schwartz*, Zmira Samra†, Hana Konigsberger†, Amos Yinnon‡, Galia Rahav§, Nathan Keller¶, Nail Bisharat#, Jehuda Karpuch**, Renato Finkelstein††, Michael Alkan‡‡, Zvi Landau§§, Julia Novikov¶¶, David Hassin##, Carlos Rudnicki†, Ruth Kitzes***, Shmouel Ovadia†††, Zvi Shimoni‡‡‡1, Ruth Lang§§§, and Tamar Shohat¶¶¶
, Rotem Levin*, Miriam Weinberger†, Yoav Golan*, David Schwartz*, Zmira Samra†, Hana Konigsberger†, Amos Yinnon‡, Galia Rahav§, Nathan Keller¶, Nail Bisharat#, Jehuda Karpuch**, Renato Finkelstein††, Michael Alkan‡‡, Zvi Landau§§, Julia Novikov¶¶, David Hassin##, Carlos Rudnicki†, Ruth Kitzes***, Shmouel Ovadia†††, Zvi Shimoni‡‡‡1, Ruth Lang§§§, and Tamar Shohat¶¶¶Table 4
Characteristics of nonperinatal listeriosis from 10 recently reported series
| First author, year (ref) |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Characteristic | McLauchlin, 1990 (8) | Gellin, 1991 (6) | Cherubin, 1991 (14) | Skogberg, 1992 (15) | Nolla-Salas, 1993 (16) | Jones, 1994 (17) | Paul, 1994 (18) | Bula, 1995 (10) | Goulet, 1996 (9) | Siegman-Igra, 2001 (present study) | Total or average |
| Country and scope | England, national | USA, six areas | USA, four centers | Finland, Helsinki | Spain, Barcelona | England, Bristol | Australia, Sydney | Switz-erland, western part | France, national | Israel, national | Worldwide |
| Study period | 1967-1985 | 1986 | 1982-1999 | 1971-1989 | 1990 | 1983-1992 | 1983-1992 | 1983-1997 | 1992 | 1995-1999 | 1967-1999 |
| Total no. of cases | 722 | 246 | 119 | 74 | 31 | 29 | 84 | 122 | 225a | 156 | 1,808 |
| Nonperinatal cases (% of total) | 474 (66%) | 179 (73%) | 54 (45%) | 58 (78%) | 29 (94%) | 16 (55%) | 71 (85%) | 57 (47%) | 225 (NA) | 87 (56%) | 1,025/1583 (65%) 1,025+225=1,250 |
| Mean age (range) (years) | 59 (1-97) | NA (<1-95) | NA | 50 (29-66) | 58 (17-89) | 60 (1-95) | 39% (>60) | 66 (31-96) | 65 (1-101) | 67 (4-91) | 50-67 |
| Male gender | 265 (58%) | 101 (56%) | NA | NA | 24 (77%) | 9 (56%) | NA | 33 (58%) | 135 (62%) | 56 (64%) | 623 (60%) |
| Peak season | Autumn and spring | Late spring to fall | May-Aug | NA | 39% in July-Sept | 76% in July-Dec | NA | NA | NA | 70% in May-Oct | Summer and fall |
| Annual incidenceb | NA | 0.7 | NA | 0.09 - 0.65 | 1.1 | 0.35 | 0.3 | NA | NA | 0.6 | 0.1-1.1 |
| Immunocompromised | 261/337 (77%) | NA | 53/54(98%) | 47/58(81%) | 24/29 (83%) | 13/16 (81%) | 59/71 (83%) | 25/57 (42%) | 159/225(71%) | 64/87 (74%) | 705/934 (74%) |
| CNS infection | 268/474 (57%) | 55/179 (31%) | 19/54 (35%) | 29/58 (50%) | 9/31 (29%) | 6/16 (37%) | 29/71 (41%) | 45/57 (79%) | 110/224(49%) | 24/87 (28%) | 594/1,251 (47%) |
| Bacteremia + focusc | 183/474 (39%) | 119/179 (66%) | 35/54 (65%) | 24/58 (41%) | 20/31 (65%) | 10/16 (73%) | 40/71 (56%) | 12/57 (21%) | 97/224 (43%) | 59/87 (68%) | 599/1,251 (48%) |
| Focal disease onlyd | 9/474 (5%) | 5/179 (3%) | - | 5/58 (8%) | 2/31 (6%) | - | 2/71 (3%) | - | 17/224 (8%) | 4/87 (5%) | 44/1,124 (4%) |
| Mortality | 164/371 (44%) | 63/179(35%) | 17/54(31%) | 15/58(26%) | 16/31 (52%) | 6/16 (37%) | 27/71 (38%) | 18/57 (32%) | 54/225 (24%) | 33/87 (38%) | 413/1,149 (36%) |
aIncludes nonperinatal cases only.
bEstimated annual incidence per 105 population.
cBacteremia with or without a non-CNS focus of infection (e.g., pneumonia, endocarditis, urinary tract infection, prostatitis, peritonitis, gastroenteritis, rectal abscess, osteomyelitis, and cellulitis).
dFor example, peritonitis, pleuritis, arthritis, pericarditis, cholecystitis, appendicitis, and cellulitis.
NA= not available; CNS= central nervous system.
1Dr. Lang died November 18, 2001.
