Volume 8, Number 3—March 2002
Research
Listeria monocytogenes Infection in Israel and Review of Cases Worldwide
Yardena Siegman-Igra*
, Rotem Levin*, Miriam Weinberger†, Yoav Golan*, David Schwartz*, Zmira Samra†, Hana Konigsberger†, Amos Yinnon‡, Galia Rahav§, Nathan Keller¶, Nail Bisharat#, Jehuda Karpuch**, Renato Finkelstein††, Michael Alkan‡‡, Zvi Landau§§, Julia Novikov¶¶, David Hassin##, Carlos Rudnicki†, Ruth Kitzes***, Shmouel Ovadia†††, Zvi Shimoni‡‡‡1, Ruth Lang§§§, and Tamar Shohat¶¶¶
, Rotem Levin*, Miriam Weinberger†, Yoav Golan*, David Schwartz*, Zmira Samra†, Hana Konigsberger†, Amos Yinnon‡, Galia Rahav§, Nathan Keller¶, Nail Bisharat#, Jehuda Karpuch**, Renato Finkelstein††, Michael Alkan‡‡, Zvi Landau§§, Julia Novikov¶¶, David Hassin##, Carlos Rudnicki†, Ruth Kitzes***, Shmouel Ovadia†††, Zvi Shimoni‡‡‡1, Ruth Lang§§§, and Tamar Shohat¶¶¶Table 5
Characteristics of perinatal listeriosis from six recently reported series
| First author, year (ref) |
|||||||
|---|---|---|---|---|---|---|---|
| Characteristic | McLauchlin, 1990 (12) | Gellin, 1991 (6) | Cherubin, 1991 (14) | Craig, 1996 (19) | Nolla-Salas, 1998 (20) | Siegman-Igra, 2001 (present study) | Total or average |
| Country and region | England, national | USA, six areas | USA, four centers | Australia, Melbourne | Spain, Barcelona | Israel, national | Worldwide |
| Study period | 1967-1985 | 1986 | 1982-1999 | 1983-1994 | 1990-1996 | 1995-1999 | 1967-1999 |
| Total no. of cases | 722 | 246 | 119 | 24a | 135 | 156 | 1,400 |
| Perinatal infection (% of total) | 248 (34%) | 67 (27%) | 65 (55%) | 24 (NA) | 21 (16%) | 69 (44%) | 470/1,378 (34%) 470+24=494 |
| Estimated incidence per 104 births | NA | 0.8-2.4 | NA | 2 | 0-4.1 | 1.4 | 0.6-4.1 |
| Average maternal age (range) (years) | NA | 26 (17-35) | NA | NA (18-39) | 30 (26-34) | 28 (21-40) | NA (26-30) |
| Early neonatal infection and survival | 114b (46%) | 31 (46%) | 20 (31%) | 14c (58%) | 11 (52%) | 19 (28%) | 209/494 (42%) |
| Late neonatal infection and survival | 36d (15%) | 8e (12%) | 21(32%) | 1d (5%) | 3d (4%) | 69/494 (14%) | |
| Infected mother and uninfected infant | 9 (4%) | 13 (19%) | 2 (3%) | 4 (17%) | 5 (23%) | 16 (23%) | 49/494 (10%) |
| Intrauterine death | 42 (17%) | 14 (21%) | 15 (23%) | 4 (17%) | 3 (14%) | 28 (41%) | 106/494 (21%) |
| Postnatal death | 47 (19%) | 1 (1%) | 7 (11%) | 2 (8%) | 1 (5%) | 3 (4%) | 61/494 (12%) |
| Gestational age at abortion (weeks) | 12-28 | 11-30 | NA | 18-29 | 10-27 | 9-26 | 9-29 |
| Immunocompromised mothers | 5 | 1 | 1 | 1 | 8f | ||
aIncludes only perinatal cases.
bIncluding 29 with unknown time of onset.
cNo differentiation between early and late neonatal infection.
d>5 days.
e>7 days.
f2 diabetes mellitus, 2 renal transplant, 2 systemic lupus erythematosus, 1 Crohn disease and steroids, 1 HIV infection.
NA= not available
1Dr. Lang died November 18, 2001.
