Emerging Infectious Disease ISSN: 1080-6059

Immunization with Heterologous Flaviviruses Protective Against Fatal West Nile Encephalitis

Robert B. Tesh

, Amelia P.A. Travassos da Rosa, Hilda Guzman, Tais P. Araujo, and Shu-Yuan Xiao

Author affiliations: University of Texas Medical Branch, Galveston, Texas, USA;

Figure

Summary of mean (±SD) West Nile virus (WNV) titers in daily blood samples from four groups of 10 hamsters each (control, Japanese encephalitis virus [JEV]-immune, St. Louis encephalitis virus [SLEV]-immune, and Yellow fever virus [YFV]-immune) after intraperitoneal inoculation of 104 tissue culture infective dose (TCID)50 of WNV. Mean virus titers are expressed as log10 TCID50/mL of blood.

Figure. Summary of mean (±SD) West Nile virus (WNV) titers in daily blood samples from four groups of 10 hamsters each (control, Japanese encephalitis virus [JEV]-immune, St. Louis encephalitis virus [SLEV]-immune, and Yellow fever virus [YFV]-immune) after intraperitoneal inoculation of 10⁴ tissue culture infective dose (TCID)₅₀ of WNV. Mean virus titers are expressed as log₁₀ TCID₅₀/mL of blood.

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