Volume 8, Number 5—May 2002
Nasopharyngeal Carriage of Streptococcus pneumoniae in Healthy Children: Implications for the Use of Heptavalent Pnemococcal Conjugate Vaccine
|Age group (% of total/age group)|
|Carriers||<2 yrs||2-5 yrs||>5 yrs||Total|
|Total carriers||26 (6.2)||132 (9.5)||84 (8.5)||242 (8.6)|
|Carriers of invasive strains||20 (74.1)||106 (81.5)||61 (71.2)||187 (77.3)|
|Carriers of strains covered by the heptavalent vaccine||19 (73.1)a||91 (68.9)b||43 (51.2)ab||153 (63.2)|
aCarriers <2 yrs vs. carriers >5 yrs: p=0.040.
bCarriers 2-5 yrs vs. carriers >5 yrs: p=0.0008.
1The Hercules Project Collaborative Group includes: F. Schettini, D. De Mattia (Bari, Italy); G. P. Salvioli, G. Faldella (Bologna, Italy); G. Caramia, E. Ruffini (Ancona, Italy); E. Reali (Cinisello Balsamo, Italy); R. Longhi (Como, Italy); G. Bona (Novara, Italy); A. Guarino, F. Albano (Napoli, Italy); R. Malvicini (Fidenza, Italy); L. Ziino (Palermo, Italy); I. Barberi, T. Corona (Messina, Italy); P. Pusceddu (Cagliari, Italy); T. Meloni (Sassari, Italy); G. Saggese, and M. Migliaccio (Pisa, Italy).
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