TY - JOUR AU - Chhour, Y. Meng AU - Ruble, Gaye AU - Hong, Rathavuth AU - Minn, Kyi AU - Kdan, Yuvatha AU - Sok, Touch AU - Nisalak, Ananda AU - Myint, Khin Saw Aye AU - Vaughn, David W. AU - Endy, Timothy P. T1 - Hospital-based Diagnosis of Hemorrhagic Fever, Encephalitis, and Hepatitis in Cambodian Children T2 - Emerging Infectious Disease journal PY - 2002 VL - 8 IS - 5 SP - 485 SN - 1080-6059 AB - Surveillance was conducted for three clinical syndromes (hemorrhagic fever, encephalitis, and hepatitis) in Cambodian children admitted to the National Pediatric Hospital in Phnom Penh from July 1996 through September 1998. Acute- and convalescent-phase sera, and cerebrospinal fluid, when applicable, underwent diagnostic evaluation for infections with Dengue virus (DENV), Japanese encephalitis virus (JEV), and Hepatitis A, B, C, and E viruses. Of 621 children admitted with hemorrhagic fever, 499 (80%) were confirmed to have either primary or secondary DENV infection. DENV rates were as high as 10.6/100 hospital admissions in September 1998. Of 50 children with clinical encephalitis, 9 (18%) had serologic evidence of JEV infection. Forty-four children had clinical hepatitis, most (55%) due to Hepatitis A virus (HAV). One patient had Hepatitis B virus, and no patients had hepatitis C or E. This study identified a large number of children with vaccine-preventable diseases (JEV and HAV). KW - Cambodia KW - dengue KW - hemorrhagic fever KW - Japanese encephalitis KW - hepatitis KW - surveillance KW - Southeast Asia DO - 10.3201/eid0805.010236 UR - https://wwwnc.cdc.gov/eid/article/8/5/01-0236_article ER - End of Reference