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Volume 8, Number 8—August 2002

Research

Genetic Characterization of Hantaviruses Transmitted by the Korean Field Mouse (Apodemus peninsulae), Far East Russia

Kumari Lokugamage*, Hiroaki Kariwa*Comments to Author , Daisuke Hayasaka*, Bai Zhong Cui*, Takuya Iwasaki†, Nandadeva Lokugamage*, Leonid I. Ivanov‡, Vladimir I. Volkov‡, Vladimir A. Demenev§, Raisa Slonova¶, Galina Kompanets¶, Tatyana Kushnaryova¶, Takeshi Kurata†, Kenji Maeda*, Koichi Araki*, Tetsuya Mizutani*, Kumiko Yoshimatsu#, Jiro Arikawa#, and Ikuo Takashima*
Author affiliations: *Hokkaido University, Sapporo, Japan; †National Institute of Infectious Diseases, Tokyo, Japan; ‡Plague Control Station, Khabarovsk, Russia; §Far Eastern Medical Association, Khabarovsk, Russia; ¶Russian Academy of Medical Sciences, Vladivostok, Russia; #Hokkaido University School of Medicine, Sapporo, Japan;

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Figure 1

Histopathologic changes in kidney tissue from a patient with hemorrhagic fever with renal syndrome, Primorye region. Changes include interstitial edema with mild infiltration of mononuclear cells (small arrow) and degeneration of renal tubules (large arrow) in cortex. Proteinaceous casts and exudate (arrowhead) are seen in lumina of renal tubules (A). No apparent glomerular changes. Most prominent change in the medulla is well–defined necrotic lesion (asterisk) (B).

Figure 1. Histopathologic changes in kidney tissue from a patient with hemorrhagic fever with renal syndrome, Primorye region. Changes include interstitial edema with mild infiltration of mononuclear cells (small arrow) and degeneration of renal tubules (large arrow) in cortex. Proteinaceous casts and exudate (arrowhead) are seen in lumina of renal tubules (A). No apparent glomerular changes. Most prominent change in the medulla is well–defined necrotic lesion (asterisk) (B).

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