Volume 8, Number 8—August 2002
Synopsis
Worldwide Occurrence of Beijing/W Strains of Mycobacterium tuberculosis: A Systematic Review
Judith R. Glynn*
, Jennifer Whiteley*, Pablo J. Bifani†, Kristin Kremer, and Dick van Soolingen
, Jennifer Whiteley*, Pablo J. Bifani†, Kristin Kremer, and Dick van SoolingenTable 2
Prevalence of Beijing and W-like strains in studies not based on spoligotypinga
| Reference | Setting | Yrs | Population | New TB or new + old | Typing methods and definitions used | Prevalence of Beijing strain N/N (%) |
|---|---|---|---|---|---|---|
| Asia | ||||||
| 23 | Henan Province, China | ? | No information given | ? | RFLP +3.6kb Pvu II fragment | 59/64 (92) |
| 23 | Philippines | ? | No information given | ? | RFLP +3.6kb Pvu II fragment | 34/34 (100) |
| 23 | Hanoi, Vietnam | ? | No information given | ? | RFLP +3.6kb Pvu II fragment | 20/50 (40) |
| 23 | Korea | 1995 | No information given | ? | RFLP +3.6kb Pvu II fragment | 99/138 (72) |
| 23 | Thailand | ? | No information given | ? | RFLP +3.6kb Pvu II fragment | 31/49 (63) |
| 24 | Bangkok Nonthaburi, Thailand | 1994–1995 | Patients from 3 hospitals ? how selected. Half extrapulmonary | ? Both | RFLP + comparison with Dutch database | 80/211 (37) |
| 23 | Malaysia | ? | No information given | ? | RFLP +3.6kb Pvu II fragment | 17/48 (35) |
| 25 | Malaysia | 1993–1994 | Random 3% sample from whole population | ? Both | RFLP “similar” to Beijing family | 83/439 (19) |
| Africa | ||||||
| 26 | Cape Town, South Africa | 1993–1997 | Whole population | Both | RFLP “strain U”, (W-like) Two closely related patterns only | 17/650 (2.6) |
| USA | ||||||
| 27 | New York City | 1992–1994 | Patients from 5 hospitals | ? Both | RFLP, strain W only | 6/302 (2.0) |
| 3 | New York City | 1990–1995 | ? selection method | ? Both | RFLP, “W-like” | 273/1,953 (14) |
| 28 | Central Los Angeles | 1994–1996 | Consecutive patients | ? Both | RFLP, strain 210 (W-related) | 43/162 (27) |
| 29 | California | 1992–1995 | All cases from specific locations | ? Both | RFLP, strain 210 (W-related) | 39/522 (7) 16/546 (3) 2/256 (0.8) |
| Texas | 1993–1995 | |||||
| Colorado | 1989–1994 | |||||
| 2 | United States (excluding NY) and Puerto Rico | 1992–1997 | All notified cases | Both | RFLP and/or PCR probe. Multidrug resistant W only | 23/104,549 (0.02) |
| South America | ||||||
| 30 | Buenaventura, Colombia | 1997–1998 | 34 treatment failure + 73 new ? selection method | Both | RFLP + PCR probe. “Similar” to W | 11/107 (10) (? 8 in new) |
aN/N, number with Beijing strain/total number of patient; ?, not clear from report; the different typing methods are described in the introduction. RFLP restriction fragment length polymorphism (RFLP) using IS6110. Polymerase chain reaction (PCR) probe is a multiplex PCR probe targeted at specific insertions. The 3.6 kb pvuII fragment was identified by IS1081 fingerprinting.
