Emerging Infectious Disease ISSN: 1080-6059

Pandrug-Resistant Acinetobacter baumannii Causing Nosocomial Infections in a University Hospital, Taiwan

Po-Ren Hsueh*, Lee-Jene Teng*, Cheng-Yi Chen*, Wen-Hwei Chen*, Shen-Wu Ho*

, and Kwen-Tay Luh*

Author affiliations: *National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan;

Results of time-kill study of two isolates of pandrug-resistant Acinetobacter baumannii (PDRAB)

	MIC (µg/mL)^a
	Isolate I	Isolate II
Antibiotic	(clone 5)	(clone 6)
Alone
Imipenem	32	32
Amikacin	128	64
Ciprofloxacin	128	2
Ampicillin-sulbactam	128	32
Combination
Imipenem + amikacin	16/64	2/4
Imipenem + ciprofloxacin	32/128	4/0.25
Imipenem + ampicillin-sulbactam	16/64	8/8
Ciprofloxacin + ampicillin-sulbactam	128/128	1/16

^aValues are the lowest concentrations (µg/mL) of each agent in combination that yielded synergy.