Mass Antibiotic Treatment for Group A Streptococcus Outbreaks in Two Long-Term Care Facilities1
Andrea Smith*†, Aimin Li‡, Ornella Tolomeo*, Gregory J. Tyrell§†, Frances Jamieson‡, and David Fisman*¶
Author affiliations: *City of Hamilton Social and Public Health Services Department, Hamilton, Ontario, Canada; †University of Alberta, Edmonton, Alberta; ‡Canada Ontario Ministry of Health and Long-Term Care, Toronto, Ontario, Canada; §Provincial Laboratory for Public Health, Edmonton, Alberta, Canada; ¶McMaster University, Hamilton, Ontario, Canada
Figure 4. Molecular epidemiology of group A streptococcal strains in outbreak 2. Pulsed-field gel electrophoresis, demonstrating relatedness of group A streptococcal isolates from facility staff and residents. Lanes 1 and 7 contain an ATCC quality control strain. Solid arrows denote identical strains from two of the three persons in whom fatal invasive group A streptococcal infection developed; the third person with invasive disease had an electrophoretically identical strain (not shown). Hollow arrows denote identical strains from persons with asymptomatic colonization with group A streptococcus. Brackets denote duplicate strains from the same person; asterisk denotes staff member.
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