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Volume 9, Number 12—December 2003

Research

Multidrug-resistant Mycobacterium tuberculosis in HIV-Infected Persons, Peru

Pablo E. Campos*†, Pedro G. Suarez‡§, Jorge Sanchez†, David Zavala‡, Jorge Arevalo‡, Eduardo Ticona‡, Charles M. Nolan*¶, Thomas M. Hooton*, and King K. Holmes*Comments to Author 
Author affiliations: *University of Washington, Seattle, Washington, USA; †Cayetano Heredia University, Lima, Peru; ‡Peruvian Ministry of Health, Lima-Peru; §Asociacion Civil Impacta Salud y Educacion (IMPACTA), Lima, Peru; ¶Public Health Seattle-King County, Seattle, Washington, USA

Main Article

Table 2

Drug-susceptibility profiles of Mycobacterium tuberculosis isolates from participants with and without known HIV infectiona

Characteristic HIV positive
HIV negative or unknown status
Patients
Interviewed patients
All patients
N (%) N (%) N (%)
Total no. tested for drug resistance
81 (100)
108 (100)
965 (100)
Fully susceptible isolates
28 (35)
92 (85)
789 (82)
Any resistance
52 (65)
16 (15)
76 (18)
Any H resistance
42 (52)
11 (10)
110 (10)
Any R resistance
39 (48)
2 (2)
53 (6)
Any E resistance
19 (24)
0 (0)
27 (3)
Any S resistance
39 (48)
12 (11)
88 (9)
Any Z resistance
28 (35)
NA
NA
Multidrug resistance
35 (43)
1 (1)
38 (3.9)
Only HR resistance
3 (4)
NA
NA
HRZ resistance
25 (32)
NA
NA
HRESZ resistance 11 (14) NA NA

aNA, not available; H, isoniazid; R, rifampin; E, ethambutol; S, streptomycin; Z, pyrazinamide; HRZ resistance includes any strain resistant at least to H and R and Z.

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