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Volume 9, Number 7—July 2003

Research

Antimicrobial Susceptibility Breakpoints and First-Step parC Mutations in Streptococcus pneumoniae: Redefining Fluoroquinolone Resistance

Sue Lim*†, Darrin Bast*†, Allison McGeer*†, Joyce de Azavedo*†, and Donald E. Low*†Comments to Author 
Author affiliations: *Toronto Medical Laboratories/Mount Sinai Hospital, Toronto, Ontario, Canada; †University of Toronto, Toronto, Ontario, Canada

Main Article

Table 3

The prevalence of ParC amino acid substitutions among all strains according to their levofloxacin and ciprofloxacin MICs

MIC (μg/mL) No. strains with ParC amino acid substitution at 79 or 83
Ciprofloxacin (%) Levofloxacin (%)
2 4/14 (29) 48/82 (59)
4 24/37 (65) 5/8 (63)
8 11/12 (92) 10/10 (100)
>8 22/22 (100) 15/15 (100)
Total 62/87 (71) 78/115 (69)

Main Article

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