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Volume 9, Number 9—September 2003

Research

Epidemic and Nonepidemic Multidrug-Resistant Enterococcus faecium

Helen L. Leavis*†, Rob J.L. Willems†, Janetta Top†, Emile Spalburg†, Ellen M. Mascini*, Ad C. Fluit*, Andy Hoepelman*, Albert J. de Neeling†, and Marc J.M. Bonten*Comments to Author 
Author affiliations: *University Medical Center Utrecht, Utrecht, the Netherlands; †National Institute of Public Health and the Environment (RIVM), Bilthoven, the Netherlands

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Table 2

Mean identification factor calculated for 92 vancomycin-susceptible Enterococcus faecium (VSEF) in clusters 1, 2, 3, and 4 to the vancomycin-resistant E. faecium (VREF) genogroups A–D

Cluster n Genogroup A
Genogroup B
Genogroup C
Genogroup D
IFa IF IF IF
1
4
1.48±0.06
1.76±0.16
2.5±0.16
3.93±0.31
2
12
2.25±0.20
1.53±0.10
2.12±0.15
3.33±0.16
3
66
2.98±0.10
1.58±0.07
1.72±0.09
3.97±0.06
4 10 3.91±0.45 2.36±0.29 1.39±0.05 4.74±0.32

aThe mean identification factor (IF) represents a measure of how well the entries of the four different VSEF clusters belong to one of the previously described VREF genogroups, taking into consideration the internal spread of the VREF genogroups. Mean identification factor was determined by calculating the arithmetic averages of identification factors of isolates of a given cluster. The lowest identification factor (indicated in boldface type) represents the highest probability that isolates in a given VSEF cluster belong to a certain VREF genogroup. The 95% confidence limits are shown for each identification factor.

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