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Volume 9, Number 9—September 2003

Research

Aseptic Meningitis Epidemic during a West Nile Virus Avian Epizootic

Kathleen G. Julian*Comments to Author , James A. Mullins†, Annette Olin‡, Heather Peters§, W. Allan Nix†, M. Steven Oberste†, Judith C. Lovchik¶, Amy Bergmann§, Ross J. Brechner§, Robert A. Myers§, Anthony A. Marfin*, and Grant L. Campbell*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA; ‡St. Matthew’s School of Medicine, Grand Caymans, British West Indies; §Maryland Department of Health and Mental Hygiene, Baltimore, Maryland, USA; ¶University of Maryland Medical Center, Baltimore, Maryland, USA

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Table 1

Descriptive summary of aseptic meningitis cases with onsets from June 1–September 30, 2001, identified at six hospitals, Baltimore, Marylanda

Cause Cases Median age
(range) % <18 y of age CSF (range)
Median leukocyte count/mL
(range) % PMN
pre-dominant Median protein
mg/dL (range)
All enterovirus meningitis cases
43
9 y
(1 wk–49 y)
70
178 (10–850)
49
48 (10–215)
Echovirus 13
15
7 y
(1 mo–49 y)
87
132 (11–650)
80
37 (18–97)
Echovirus 18
11
17 y
(2 mo–35 y)
55
173 (12–409)
27
44 (16–215)
Coxsackievirus B2
5
19 y
(1 wk–31 y)
40
250 (45–850)
0
87 (57–120)
Echovirus 6
2
33 y
(31–34 y)
0
330 (130–530)
50
56 (52–59)
Echovirus 30
1
10 y
1
10
0
18
Untyped enterovirus
9
9 y
(1 mo–20 y)
89
178 (43–850)
56
48 (10–153)
Herpes simplex virus meningitis cases
2
39 y
(29–49 y)
0
246 (136–355)
0
128 (77–179)
Lyme meningitis case
1
74 y
0
227
0
143
Cases of undetermined cause
67
25 y
(2 wk–67 y)
39
100 (7–1083)
38b
53c (19–209)
Total cases 113 18 y
(1 wk–74 y) 50 135 (7–1083) 41d 53e(10-215)

aCSF, cerebrospinal fluid; PMN, polymorphonuclear cells.
bN=64.
cN=65.
dN=110.
eN=111.

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