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Volume 10, Number 8—August 2004
Research

Thrombocytopenia and Acute Renal Failure in Puumala Hantavirus Infections

Franz Maximilian Rasche*Comments to Author , Boris Uhel*, Rainer G. Ulrich†, Detlev H. Krüger†, Wolfram Karges*, David Czock*, Walter Hampl*, Frieder Keller*, Helga Meisel†, and Lutz von Müller*
Author affiliations: *University Hospital Ulm, Ulm, Germany; †Charité, Berlin, Germany

Main Article

Table 2

Virologic results of 15 patients with acute PUUV infection

Patient IgG-EIA (Progen) index IgG titers IgM titers c-FRNT titers

PUUV
PUUV
HTNV
DOBV
PUUV
PUUV
HTNV
DOBV
SEOV
TULV
1
9
6,400
Neg
Neg
3,200
640
<40
160
<40
160
2
2.1
2,560
640

2,560





3
2.2
6,400
400
400
1,600
2,560
<40
<40
<40
40
4
3.3
51,200
6,400
400
12,800
640
160
40
<40
160
5
3.8
51,200
3,200
Neg
bPos
2,560
160
40
<40
40
6
3.1
6,400
800
Neg
6,400
2,560
640
40
<40
160
7
3.1
12,800
800
Neg
1,280
640
<40
<40

40
8
4.3
12,800
3,200
800
3,200
2,560
160
40
<40
160
9
1.8
cPos


cPos





10
2.9
12,800
3,200
3,200
400
2,560
160
40
<40
160
11
7.1
12,800
1,600
400
1,600





12
2.9
cPos


cPos





13
4.9
51,200
400
Neg
3,200





14
2.5
cPos


cPos





15 3.3 12,800 1,600 400 1,600 2,560 40 <40 40 40

aPUUV, Puumala virus; Ig, immunoglobulin; EIA, enzyme immunoassay; c-FRNT, chemiluminescence focus reduction neutralization assays; HTNV, Hantaan virus; DOBV, Dobrava virus; SEOV, Seoul virus; TULV, Tula virus; –, not available.
bIgM-EIA (Progen, Heidelberg, Germany).
cImmunoblot (Mikrogene, Martinsried, Germany).

Main Article

Page created: March 02, 2011
Page updated: March 02, 2011
Page reviewed: March 02, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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