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Volume 15, Number 7—July 2009
Research

Clusters of Multidrug-Resistant Mycobacterium tuberculosis Cases, Europe

Isabelle DevauxComments to Author , Kristin Kremer, Herre Heersma, and Dick van Soolingen
Author affiliations: European Centre for Disease Prevention and Control, Stockholm, Sweden (I. Devaux); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (K. Kremer, H. Heersma, D. Van Soolingen)

Main Article

Table 5

Predictors for TB caused by Beijing strains among 506 cases reported in 16 European countries, January 2003 through June 2007*

Variable MDR TB strains
Unadjusted OR (95% CI) Adjusted† OR (95% CI)
No. patients % Beïjing strains
Sex
Male 333 58 1 1
Female
164
55
0.9 (0.6–1.3)
1.1 (0.5–2.4)
Age
15–44 313 53 1 1
45–64 142 67 1.7 (1.1–2.6) 1.0 (0.5–2.1)
>65
30
70
2.5 (1.1–5.5)
2.3 (0.5–10.4)
Origin
Baltic states 188 92 154.5 (54.0–442.0) 173.8 (45.5–663.6)
Other FSU countries‡ 99 75 39.7 (14.4–109.5) 32.2 (8.6–120.8)
Other European countries 71 6 1 1
Africa
71
10
1.5 (0.4–4.9)
1.1 (0.2–5.5)
Site of disease
Pulmonary 455 59 3.4 (1.7–6.6) 0.7 (0.1–3.3)
Extrapulmonary
40
30
1
1
Previous TB
Yes 156 64 1.1 (0.8–1.7) 1.0 (0.5–2.0)
No
245
62
1
1
Clustering
Yes 250 87% 19.0 (12.0–30.3)
No
250
26%
1

XDR TB
Yes 51 90 5.5 (2.1–14.3)
No 341 62 1

*TB, tuberculosis; MDR, multidrug-resistant; OR, odds ratio; CI, confidence interval; FSU, former Soviet Union; XDR, extensively drug-resistant. Boldface indicates significance.
†For all other factors in the model except XDR TB.
‡Former Soviet Union countries: Azerbaijan, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Ukraine, and Uzbekistan.

Main Article

Page created: November 08, 2010
Page updated: November 08, 2010
Page reviewed: November 08, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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