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Volume 8, Number 11—November 2002
THEME ISSUE
Tuberculosis Genotyping
Tuberculosis Genotyping Network, United States

Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern

Kerry H. Lok*, William H. Benjamin*, Michael E. Kimerling*Comments to Author , Virginia Pruitt†, Donna Mulcahy†, Nancy Robinson†, Nancy B. Keenan†, and Nancy E. Dunlap*
Author affiliations: *University of Alabama School of Medicine, Birmingham, Alabama, USA; †Alabama Department of Public Health, Montgomery, Alabama, USA;

Main Article

Table

Comparison of a common two-band IS6110 RFLP pattern with spoligotyping and VNTRa

Spoligotyping VNTR Related to conventional outbreak
Octal (CDC designation)
No. of isolates
VNTR results
(AL designation)
No. of isolates
Store
Bus
Homeless
777776777760601(0009) 55 6,3,2,4,2,3,2 (01) 22 2
6,3,2,3,2,2,2 (02) 12 4 4
6,3,2,4,2,3,3 (03) 8 2
6,3,2,3,2,2,3 (04) 4 3
6,3,2,2,2,2,2 (05) 3 3
6,3,2,3,2,3,2 (06) 2
6,3,2,3,2,3,3 (07) 2 1
6,3,2,4,2,2,2 (08) 1
6,2,2,3,2,2,2 (09) 1 1
037776777760601(0545) 14 6,3,2,3,2,4,2 (10) 14 14
777776777760771(0003) 12 6,3,2,2,2,1,2 (11) 7 5
6,3,2,3,2,3,2.5 (12) 1
6,3,2,2,2,1,3 (13) 1
6,3,1,2,2,2,3 (14) 1 1
6,3,2,3,2,2,2 (02) 1 1
6,3,2,3,2,3,3 (07) 1
001776777760601(0550) 3 6,3,2,4,2,3,2 (01) 3
777776374360711(1445) 1 6,3,2,1,2,3,2.5 (15) 1 1
037766677760601(n/a) 1 6,3,2,3,2,4,2 (10) 1 1
Total 86 86 15 4 24

aRFLP, restriction fragment length polymorphism; VNTR, variable number of tandem repeats, CDC, Centers for Disease Control and Prevention.

Main Article

Page created: July 19, 2010
Page updated: July 19, 2010
Page reviewed: July 19, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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