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Charbon pulmonaire d’origine bioterroriste: les 10 premiers cas rapportés aux Etats-Unis

John A. Jernigan*, David S. Stephens*†, David A. Ashford*, Carlos Omenaca‡, Martin S. Topiel§, Mark Galbraith¶, Michael Tapper#, Tamara L. Fisk*†, Sherif Zaki*, Tanja Popovic*, Richard F. Meyer*, Conrad P. Quinn*, Scott A. Harper*, Scott K. Fridkin*, James J. Sejvar*, Colin W. Shepard*, Michelle McConnell*, Jeannette Guarner*, Wun-Ju Shieh*, Jean M. Malecki**, Julie L. Gerberding*, James M. Hughes*, Bradley A. Perkins*, and members of the Anthrax Bioterrorism Investigation Team

Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA;; †Emory University School of Medicine, Atlanta, Georgia, USA;; ‡Cedars Medical Center, Miami, Florida, USA;; §Virtua Health, Mount Holly, New Jersey, USA;; ¶Winchester Medical Center, Winchester, Virginia, USA;; #Lenox Hill Hospital, New York City, New York, USA;; **Palm Beach County Department of Public Health, West Palm Beach, Florida, USA


Article in English

l'Article Principal

Figure 7

A. Pleural fluid cell block from a nonfatal case showing abundant Bacillus anthracis granular antigen staining inside mononuclear inflammatory cells. (Immunohistochemical assay with a mouse monoclonal anti-B. anthracis capsule antibody and detection with alkaline phosphatase and naphthol fast red, original magnification 158X). B. Mediastinal lymph node from a fatal case of anthrax showing extensive capsular and sinusoidal hemorrhage. (Hematoxylin and eosin, original magnification 25X). C. Lymph

Figure 7A. Culot de cellules de liquide pleural dans un cas non mortel, montrant la coloration de nombreux antigènes granulaires de Bacillus anthracis à l’intérieur de mononucléaires inflammatoires (Dosage immunohistochimique par anticorps monoclonal murin de capsule de B. anthracis et détection par  phosphatase alcaline et rouge naphtol, grossi 158 fois). B. Ganglion médiastinal dans un cas mortel de maladie du charbon  montrant la présence d’une importante hémorragie sous-capsulaire et sinusoïde. (Hématoxyline et éosine, grossi 25 fois). C. Ganglion chez le même patient que 7B, montrant la coloration de nombreux antigènes granulaires de Bacillus anthracis à l’intérieur de mononucléaires inflammatoires et des bacilles (flèches) dans la zone hémorragique sous-capsulaire. (Dosage immunohistochimique par anticorps monoclonal murin de paroi de B. anthracis et détection par  phosphatase alcaline et rouge naphtol, grossi 100 fois). D. Tissu pulmonaire dans un cas mortel, montrant la coloration d’antigènes granulaires de Bacillus anthracis à l’intérieur d’un macrophage périhilaire (flèche rouge) et de bacilles  intra- et extracellulaires (flèche noire). (Dosage immunohistochimique par anticorps monoclonal murin de paroi de B. anthracis et détection par  phosphatase alcaline et rouge naphtol, grossi 100 fois).

l'Article Principal

1Members of the team who contributed to the work presented in this manuscript are J. Aguilar, M. Andre, K. Baggett, B. Bell, D. Bell, M. Bowen, G. Carlone, M. Cetron, S. Chamany, B. De, C. Elie, M. Fischer, A. Hoffmaster, K. Glynn, R. Gorwitz, C. Greene, R. Hajjeh, T. Hilger, J. Kelly, R. Khabbaz, A. Khan, P. Kozarsky, M. Kuehnert, J. Lingappa, C. Marston, J. Nicholson, S. Ostroff, T. Parker, L. Petersen, R. Pinner, N. Rosenstein, A. Schuchat, V. Semenova, S. Steiner, F. Tenover, B. Tierney, T. Uyeki, S. Vong, D. Warnock, C. Spak, D. Jernigan, C. Friedman, M. Ripple, D. Patel, S. Pillai, S. Wiersma, R. Labinson, L. Kamal, E. Bresnitz, M. Layton, G. DiFerdinando, S. Kumar, P. Lurie, K. Nalluswami, L. Hathcock, L. Siegel, S. Adams, I. Walks, J. Davies-Coles, M. Richardson, K. Berry, E. Peterson, R. Stroube, H. Hochman, M. Pomeranz, A. Friedman-Kien, D. Frank, S. Bersoff-Matcha, J. Rosenthal, N. Fatteh, A. Gurtman, R. Brechner, C. Chiriboga, J. Eisold, G. Martin, K. Cahill, R. Fried, M. Grossman, and W. Borkowsky.

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Page created: August 03, 2011
Page updated: August 03, 2011
Page reviewed: August 03, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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