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Charbon pulmonaire d’origine bioterroriste: les 10 premiers cas rapportés aux Etats-Unis

John A. Jernigan*, David S. Stephens*†, David A. Ashford*, Carlos Omenaca‡, Martin S. Topiel§, Mark Galbraith¶, Michael Tapper#, Tamara L. Fisk*†, Sherif Zaki*, Tanja Popovic*, Richard F. Meyer*, Conrad P. Quinn*, Scott A. Harper*, Scott K. Fridkin*, James J. Sejvar*, Colin W. Shepard*, Michelle McConnell*, Jeannette Guarner*, Wun-Ju Shieh*, Jean M. Malecki**, Julie L. Gerberding*, James M. Hughes*, Bradley A. Perkins*, and members of the Anthrax Bioterrorism Investigation Team
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Emory University School of Medicine, Atlanta, Georgia, USA; ‡Cedars Medical Center, Miami, Florida, USA; §Virtua Health, Mount Holly, New Jersey, USA; ¶Winchester Medical Center, Winchester, Virginia, USA; #Lenox Hill Hospital, New York City, New York, USA; **Palm Beach County Department of Public Health, West Palm Beach, Florida, USA

Article in English

l'Article Principal

Tableau 3

Résultats des premiers examens cliniques effectués chez les 10 patients atteints de charbon pulmonaire d’origine bioterroriste, octobre - novembre 2001

Examen clinique
Fièvre (>37.8°C) 7/10
  Tachycardie (rythme cardiaque >100/min) 8/10
  Hypotension (pression systolique <110 mm Hg) 1/10
Examens de laboratoire
  Nombre de globules blancs (valeur médiane, extrêmes) 9.8 x 103/mm3
  Formule leucocytaire - polynucléose neutrophile (>70%) 7/10
  Métamyélocytes (>5%) 4/5
  Elevated transaminasesa 9/10
  (ASAT ou ALAT > 40)
  Hypoxémie 6/10
  (Gradient alveolo-artériel de pression d’oxygène >30 mm Hg à l’O2 ambiant <94%)
  Acidose métabolique 2/10
Elévation de la créatinine (>1.5 mg/dL) 1/10
Résultats de la radiographie thoracique
  Présence d’une anomalie 10/10
  Elargissement du médiastin 7/10
  Infiltrats/consolidations 7/10
  Epanchement pleural 8/10
Résultats de la tomodensitométrie
  Présence d’une anomalie 8/8
  Adénopathies médiastinales, élargissement du médiastin 7/8
  Epanchement pleural 8/8
  Infiltrats, consolidations 6/8

ASAT = transaminases glutamiques oxalo-acétiques sériques; ALAT = transaminases glutamiques pyruviques sériques

l'Article Principal

1Members of the team who contributed to the work presented in this manuscript are J. Aguilar, M. Andre, K. Baggett, B. Bell, D. Bell, M. Bowen, G. Carlone, M. Cetron, S. Chamany, B. De, C. Elie, M. Fischer, A. Hoffmaster, K. Glynn, R. Gorwitz, C. Greene, R. Hajjeh, T. Hilger, J. Kelly, R. Khabbaz, A. Khan, P. Kozarsky, M. Kuehnert, J. Lingappa, C. Marston, J. Nicholson, S. Ostroff, T. Parker, L. Petersen, R. Pinner, N. Rosenstein, A. Schuchat, V. Semenova, S. Steiner, F. Tenover, B. Tierney, T. Uyeki, S. Vong, D. Warnock, C. Spak, D. Jernigan, C. Friedman, M. Ripple, D. Patel, S. Pillai, S. Wiersma, R. Labinson, L. Kamal, E. Bresnitz, M. Layton, G. DiFerdinando, S. Kumar, P. Lurie, K. Nalluswami, L. Hathcock, L. Siegel, S. Adams, I. Walks, J. Davies-Coles, M. Richardson, K. Berry, E. Peterson, R. Stroube, H. Hochman, M. Pomeranz, A. Friedman-Kien, D. Frank, S. Bersoff-Matcha, J. Rosenthal, N. Fatteh, A. Gurtman, R. Brechner, C. Chiriboga, J. Eisold, G. Martin, K. Cahill, R. Fried, M. Grossman, and W. Borkowsky.

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Page created: August 04, 2011
Page updated: August 04, 2011
Page reviewed: August 04, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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