TY - JOUR AU - Knowles, Nick AU - Samuel, Alan AU - Davies, Paul AU - Midgley, Rebecca AU - Valarcher, Jean-François T1 - Pandemic Strain of Foot-and-Mouth Disease Virus Serotype O T2 - Emerging Infectious Disease journal PY - 2005 VL - 11 IS - 12 SP - 1887 SN - 1080-6059 AB - A particular genetic lineage of foot-and-mouth disease virus (FMDV) serotype O, which we have named the PanAsia strain, was responsible for an explosive pandemic in Asia and extended to parts of Africa and Europe from 1998 to 2001. In 2000 and 2001, this virus strain caused outbreaks in the Republic of Korea, Japan, Russia, Mongolia, South Africa, the United Kingdom, Republic of Ireland, France, and the Netherlands, countries which last experienced FMD outbreaks decades before (ranging from 1934 for Korea to 1984 for the Netherlands). Although the virus has been controlled in all of these normally FMD-free or sporadically infected countries, it appears to be established throughout much of southern Asia, with geographically separated lineages evolving independently. A pandemic such as this is a rare phenomenon but demonstrates the ability of newly emerging FMDV strains to spread rapidly throughout a wide region and invade countries previously free from the disease. KW - Aphthovirus KW - Epidemiology, Molecular KW - Foot-and-Mouth Disease Virus KW - Molecular Sequence Data KW - Phylogeny KW - Picornaviridae, Research DO - 10.3201/eid1112.050908 UR - https://wwwnc.cdc.gov/eid/article/11/12/05-0908_article ER - End of Reference