TY - JOUR AU - Rainbow, Jean AU - Cebelinski, Elizabeth AU - Bartkus, Joanne AU - Glennen, Anita AU - Boxrud, Dave AU - Lynfield, Ruth T1 - Rifampin-resistant Meningococcal Disease T2 - Emerging Infectious Disease journal PY - 2005 VL - 11 IS - 6 SP - 977 SN - 1080-6059 AB - Rifampin-resistant meningococcal disease occurred in a child who had completed rifampin chemoprophylaxis for exposure to a sibling with meningococcemia. Susceptibility testing of 331 case isolates found only 1 other case of rifampin-resistant disease in Minnesota, USA, during 11 years of statewide surveillance. Point mutations in the RNA polymerase β subunit (rpoB) gene were found in isolates from each rifampin-resistant case-patient. KW - Keywords: Antibiotic resistance KW - Neisseria meningitidis KW - meningococcal infections KW - chemoprophylaxis KW - rifampin KW - RNA polymerase beta subunit KW - United States DO - 10.3201/eid1106.050143 UR - https://wwwnc.cdc.gov/eid/article/11/6/05-0143_article ER - End of Reference