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Volume 12, Number 12—December 2006
Perspective
On the Question of Sporadic or Atypical Bovine Spongiform Encephalopathy and Creutzfeldt-Jakob Disease
Paul Brown*
, Lisa M. McShane†, Gianluigi Zanusso‡, and Linda Detwiler§
, Lisa M. McShane†, Gianluigi Zanusso‡, and Linda Detwiler§
Figure 5
Figure 5. Diagram of 2 possible informative trends in the incidence of bovine spongiform encephalopathy (BSE) and Creutzfeld-Jakob disease (CJD). The left panel shows the likely trends of typical BSE and variant CJD (vCJD). The right upper panel shows 1 possible pair of trends of atypical BSE and sporadic CJD (sCJD) that might occur in conjunction with the typical BSE/vCJD trends, and would be consistent with the interpretation that atypical BSE is not sporadic and is not related to sCJD. The right lower panel shows a second possible associated pair of trends consistent with the interpretation that atypical BSE is sporadic and might also be related to the type 2 M/V subset of apparently sCJD.
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