TY - JOUR AU - Faye, Ousmane AU - Diallo, Mawlouth AU - Diop, Djibril AU - Bezeid, O. Elmamy AU - Bâ, Hampathé AU - Niang, Mbayame AU - Dia, Ibrahima AU - Mohamed, Sid Ahmed Ould AU - Ndiaye, Kader AU - Diallo, Diawo AU - Ly, Peinda Ogo AU - Diallo, Boubacar AU - Nabeth, Pierre AU - Simon, François AU - Lô, Baïdy AU - Diop, Ousmane Madiagne T1 - Rift Valley Fever Outbreak with East-Central African Virus Lineage in Mauritania, 2003 T2 - Emerging Infectious Disease journal PY - 2007 VL - 13 IS - 7 SP - 1016 SN - 1080-6059 AB - In October 2003, 9 human cases of hemorrhagic fever were reported in 3 provinces of Mauritania, West Africa. Test results showed acute Rift Valley fever virus (RVFV) infection, and a field investigation found recent circulation of RVFV with a prevalence rate of 25.5% (25/98) and 4 deaths among the 25 laboratory-confirmed case-patients. Immunoglobulin M against RVFV was found in 46% (25/54) of domestic animals. RVFV was also isolated from the mosquito species Culex poicilipes. Genetic comparison of virion segments indicated little variation among the strains isolated. However, phylogenetic studies clearly demonstrated that these strains belonged to the East-Central African lineage for all segments. To our knowledge, this is the first time viruses of this lineage have been observed in an outbreak in West Africa. Whether these strains were introduced or are endemic in West Africa remains to be determined. KW - Rift Valley fever KW - outbreak KW - virus lineage KW - emergence KW - field investigations KW - human KW - animals KW - mosquitoes KW - research KW - Mauritania DO - 10.3201/eid1307.061487 UR - https://wwwnc.cdc.gov/eid/article/13/7/06-1487_article ER - End of Reference