TY - JOUR AU - Bruce, Michael G. AU - Deeks, Shelley L. AU - Zulz, Tammy AU - Bruden, Dana AU - Navarro, Christine AU - Lovgren, Marguerite AU - Jette, Louise AU - Kristinsson, Karl AU - Sigmundsdottir, Gudrun AU - Jensen, Knud Brinkløv AU - Lovoll, Oistein AU - Nuorti, J. Pekka AU - Herva, Elja AU - Nystedt, Anders AU - Sjostedt, Anders AU - Koch, Anders AU - Hennessy, Thomas W. AU - Parkinson, Alan J. T1 - International Circumpolar Surveillance System for Invasive Pneumococcal Disease, 1999–2005 T2 - Emerging Infectious Disease journal PY - 2008 VL - 14 IS - 1 SP - 25 SN - 1080-6059 AB - The International Circumpolar Surveillance System is a population-based surveillance network for invasive bacterial disease in the Arctic. The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced for routine infant vaccination in Alaska (2001), northern Canada (2002–2006), and Norway (2006). Data for invasive pneumococcal disease (IPD) were analyzed to identify clinical findings, disease rates, serotype distribution, and antimicrobial drug susceptibility; 11,244 IPD cases were reported. Pneumonia and bacteremia were common clinical findings. Rates of IPD among indigenous persons in Alaska and northern Canada were 43 and 38 cases per 100,000 population, respectively. Rates in children <2 years of age ranged from 21 to 153 cases per 100,000 population. In Alaska and northern Canada, IPD rates in children <2 years of age caused by PCV7 serotypes decreased by >80% after routine vaccination. IPD rates are high among indigenous persons and children in Arctic countries. After vaccine introduction, IPD caused by non-PCV7 serotypes increased in Alaska. KW - Streptococcus pneumoniae KW - invasive pneumococcal disease KW - IPD KW - surveillance KW - PCV7 KW - serotype replacement KW - indigenous KW - Alaska Native KW - circumpolar KW - arctic KW - research KW - United States KW - Canada KW - Greenland KW - Iceland KW - Norway KW - Sweden KW - Finland DO - 10.3201/eid1401.071315 UR - https://wwwnc.cdc.gov/eid/article/14/1/07-1315_article ER - End of Reference