TY - JOUR AU - Aiki-Raji, Comfort O. AU - Aguilar, Patricia V. AU - Kwon, Yong-Kuk AU - Goetz, Sue AU - Suarez, David L. AU - Jethra, Aashish I. AU - Nash, Oyekanmi AU - Adeyefa, Christopher A.O. AU - Adu, Festus D. AU - Swayne, David AU - Basler, Christopher F. T1 - Phylogenetics and Pathogenesis of Early Avian Influenza Viruses (H5N1), Nigeria T2 - Emerging Infectious Disease journal PY - 2008 VL - 14 IS - 11 SP - 1753 SN - 1080-6059 AB - Three highly pathogenic avian influenza subtype H5N1 and 4 Newcastle disease viruses were isolated from sick or dead chickens in southwestern Nigeria. Sequencing and phylogenetic analysis placed them within H5N1 subclade 2.2.2. Intravenous and intranasal pathogenicity tests produced systemic disease with vascular endothelial cell tropism in chickens. KW - Africa KW - H5N1 KW - influenza KW - Nigeria KW - pathotyping KW - phylogenetic analysis KW - dispatch DO - 10.3201/eid1411.080557 UR - https://wwwnc.cdc.gov/eid/article/14/11/08-0557_article ER - End of Reference