TY - JOUR AU - Zhang, Yong-Zhen AU - Zhang, Feng-Xian AU - Gao, Na AU - Wang, Jian-Bo AU - Zhao, Zhi-Wei AU - Li, Ming-Hui AU - Chen, Hua-Xin AU - Zou, Yang AU - Plyusnin, Alexander T1 - Hantaviruses in Rodents and Humans, Inner Mongolia Autonomous Region, China T2 - Emerging Infectious Disease journal PY - 2009 VL - 15 IS - 6 SP - 885 SN - 1080-6059 AB - Surveys were carried out in 2003–2006 to better understand the epidemiology of hantaviruses in the Inner Mongolia Autonomous Region of China (Inner Mongolia). Hemorrhagic fever with renal syndrome (HFRS) was first reported in this region in 1955 and has been an important public health problem here since then. During 1955–2006, 8,309 persons with HFRS were reported in Inner Mongolia (average incidence rate 0.89/100,000), and 261 (3.14%) died. Before the 1990s, all HFRS cases occurred in northeastern Inner Mongolia. Subsequently, HFRS cases were registered in central (1995) and western (1999) Inner Mongolia. In this study, hantaviral antigens were identified in striped field mice (Apodemus agrarius) from northeastern Inner Mongolia and in Norway rats (Rattus norvegicus) from middle and western Inner Mongolia. Phylogenetic analysis of hantaviral genome sequences suggests that HFRS has been caused mainly by Hantaan virus in northeastern Inner Mongolia and by Seoul virus in central and western Inner Mongolia. KW - Viruses KW - zoonoses KW - hemorrhagic fever with renal syndrome KW - hantavirus KW - Hantaan virus KW - Seoul virus KW - China KW - Mongolia KW - research DO - 10.3201/eid1506.081126 UR - https://wwwnc.cdc.gov/eid/article/15/6/08-1126_article ER - End of Reference