TY - JOUR AU - Bardhan, Pradip AU - Faruque, A.S.G. AU - Naheed, Aliya AU - Sack, David A. T1 - Decreasing Shigellosis-related Deaths without Shigella spp.–specific Interventions, Asia T2 - Emerging Infectious Disease journal PY - 2010 VL - 16 IS - 11 SP - 1718 SN - 1080-6059 AB - In 1999, a review of the literature for 1966–1997 suggested that ≈1.1 million persons die annually of shigellosis, including ≈880,000 in Asia. Our recent review of the literature for 1990–2009 indicates that ≈125 million shigellosis cases occur annually in Asia, of which ≈14,000 are fatal. This estimate for illnesses is similar to the earlier estimate, but the number of deaths is 98% lower; that is, the lower estimate of deaths is associated with markedly reduced case-fatality rates rather than fewer cases. Shigella spp.–related deaths decreased substantially during a period without Shigella spp.–specific interventions. We speculate that nonspecific interventions, e.g., measles vaccination, vitamin A supplementation, and improved nutrition, may have led to the reduced number of shigellosis-related deaths. KW - Bacteria KW - enteric infections KW - Shigella KW - shigellosis KW - mortality KW - Asia KW - Bangladesh KW - measles vaccine KW - vitamin A KW - research DO - 10.3201/eid1611.090934 UR - https://wwwnc.cdc.gov/eid/article/16/11/09-0934_article ER - End of Reference