TY - JOUR AU - Wang, Leyi AU - Ding, Zhengrong AU - Wang, Huiling AU - Li, Liqun AU - Pang, Yankun AU - Brown, Kevin E. AU - Xu, Songtao AU - Zhu, Zhen AU - Rota, Paul A. AU - Featherstone, David AU - Deng, Ying T1 - New Measles Virus Genotype Associated with Outbreak, China T2 - Emerging Infectious Disease journal PY - 2010 VL - 16 IS - 6 SP - 943 SN - 1080-6059 AB - To determine the origin of the virus associated with a measles outbreak in Menglian County, Yunnan Province, People’s Republic of China, in 2009, we conducted genetic analyses. Phylogenetic analyses based on nucleoprotein (N) and hemagglutinin (H) gene sequences showed that these Menglian viruses were not closely related to sequences of any World Health Organization (WHO) reference strains representing the 23 currently recognized genotypes. The minimum nucleotide divergence between the Menglian viruses and the most closely related reference strain, genotype D7, was 3.3% for the N gene and 3.0% for the H gene. A search of the databases of GenBank, WHO, and the Health Protection Agency Measles Nucleotide Surveillance showed that the Menglian viruses, together with the 2 older non-Menglian viruses, could be members of a new proposed measles genotype, d11. The new genotype designation will allow for better description of measles transmission patterns, especially in the Southeast Asian and Western Pacific regions. KW - Measles virus KW - new genotype KW - phylogenetic analysis KW - viruses KW - research KW - China DO - 10.3201/eid1606.100089 UR - https://wwwnc.cdc.gov/eid/article/16/6/10-0089_article ER - End of Reference