TY - JOUR AU - Kreisel, Kristen M. AU - Johnson, J. Kristie AU - Stine, O. Colin AU - Shardell, Michelle D. AU - Perencevich, Eli N. AU - Lesse, Alan J. AU - Gordin, Fred M. AU - Climo, Michael W. AU - Roghmann, Mary-Claire T1 - Illicit Drug Use and Risk for USA300 Methicillin-Resistant Staphylococcus aureus Infections with Bacteremia T2 - Emerging Infectious Disease journal PY - 2010 VL - 16 IS - 9 SP - 1419 SN - 1080-6059 AB - To assess the association of illicit drug use and USA300 methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, a multicenter study was conducted at 4 Veterans Affairs medical centers during 2004–2008. The study showed that users of illicit drugs were more likely to have USA300 MRSA bacteremia (in contrast to bacteremia caused by other S. aureus strains) than were patients who did not use illicit drugs (adjusted relative risk 3.0; 95% confidence interval 1.9–4.4). The association of illicit drug use with USA300 MRSA bacteremia decreased over time (p = 0.23 for trend). Notably, the proportion of patients with USA300 MRSA bacteremia who did not use illicit drugs increased over time. This finding suggests that this strain has spread from users of illicit drugs to other populations. KW - Staphylococcus aureus KW - antimicrobial resistance KW - community-acquired infections KW - bacteremia KW - bacterial typing techniques KW - electrophoresis KW - bacteria KW - illicit drug use KW - research KW - United States DO - 10.3201/eid1609.091802 UR - https://wwwnc.cdc.gov/eid/article/16/9/09-1802_article ER - End of Reference