TY - JOUR AU - Tracy, LaRee A. AU - Furuno, Jon P. AU - Harris, Anthony D. AU - Singer, Mary AU - Langenberg, Patricia AU - Roghmann, Mary-Claire T1 - Staphylococcus aureus Infections in US Veterans, Maryland, USA, 1999–2008 T2 - Emerging Infectious Disease journal PY - 2011 VL - 17 IS - 3 SP - 441 SN - 1080-6059 AB - Trends in Staphylococcus aureus infections are not well described. To calculate incidence in overall S. aureus infection and invasive and noninvasive infections according to methicillin susceptibility and location, we conducted a 10-year population-based retrospective cohort study (1999–2008) using patient-level data in the Veterans Affairs Maryland Health Care System. We found 3,674 S. aureus infections: 2,816 (77%) were noninvasive; 2,256 (61%) were methicillin-resistant S. aureus (MRSA); 2,517 (69%) were community onset, and 1,157 (31%) were hospital onset. Sixty-one percent of noninvasive infections were skin and soft tissue infections; 1,112 (65%) of these were MRSA. Ten-year averaged incidence per 100,000 veterans was 749 (± 132 SD, range 549–954) overall, 178 (± 41 SD, range 114–259) invasive, and 571 (± 152 SD, range 364–801) noninvasive S. aureus infections. Incidence of all S. aureus infections significantly increased (p<0.001), driven by noninvasive, MRSA, and community-onset infections (p<0.001); incidence of invasive S. aureus infection significantly decreased (p<0.001). KW - Staphylococcus aureus KW - methicillin resistance KW - community-acquired KW - bacteria KW - infections KW - CME KW - staphylococci KW - skin infections KW - veterans KW - research KW - Maryland KW - USA KW - United States DO - 10.3201/eid1703.100502 UR - https://wwwnc.cdc.gov/eid/article/17/3/10-0502_article ER - End of Reference