TY - JOUR AU - McMullen, Allison R. AU - May, Fiona J. AU - Li, Li AU - Guzman, Hilda AU - Bueno, Rudy AU - Dennett, James A. AU - Tesh, Robert B. AU - Barrett, Alan D.T. T1 - Evolution of New Genotype of West Nile Virus in North America T2 - Emerging Infectious Disease journal PY - 2011 VL - 17 IS - 5 SP - 785 SN - 1080-6059 AB - Previous studies of North American isolates of West Nile virus (WNV) during 1999–2005 suggested that the virus had reached genetic homeostasis in North America. However, genomic sequencing of WNV isolates from Harris County, Texas, during 2002–2009 suggests that this is not the case. Three new genetic groups have been identified in Texas since 2005. Spread of the southwestern US genotype (SW/WN03) from the Arizona/Colorado/northern Mexico region to California, Illinois, New Mexico, New York, North Dakota, and the Texas Gulf Coast demonstrates continued evolution of WNV. Thus, WNV continues to evolve in North America, as demonstrated by selection of this new genotype. Continued surveillance of the virus is essential as it continues to evolve in the New World. KW - West Nile virus KW - viruses KW - North America KW - evolution KW - genotype KW - genomic sequences KW - research KW - United States DO - 10.3201/eid1705.101707 UR - https://wwwnc.cdc.gov/eid/article/17/5/10-1707_article ER - End of Reference