TY - JOUR AU - Katchanov, Juri AU - Sawanyawisuth, Kittisak AU - Chotmongkol, Verajit AU - Nawa, Yukifumi T1 - Neurognathostomiasis, a Neglected Parasitosis of the Central Nervous System T2 - Emerging Infectious Disease journal PY - 2011 VL - 17 IS - 7 SP - 1174 SN - 1080-6059 AB - Gnathostomiasis is a foodborne zoonotic helminthic infection caused by the third-stage larvae of Gnathostoma spp. nematodes. The most severe manifestation involves infection of the central nervous system, neurognathostomiasis. Although gnathostomiasis is endemic to Asia and Latin America, almost all neurognathostomiasis cases are reported from Thailand. Despite high rates of illness and death, neurognathostomiasis has received less attention than the more common cutaneous form of gnathostomiasis, possibly because of the apparent geographic confinement of the neurologic infection to 1 country. Recently, however, the disease has been reported in returned travelers in Europe. We reviewed the English-language literature on neurognathostomiasis and analyzed epidemiology and geographic distribution, mode of central nervous system invasion, pathophysiology, clinical features, neuroimaging data, and treatment options. On the basis of epidemiologic data, clinical signs, neuroimaging, and laboratory findings, we propose diagnostic criteria for neurognathostomiasis. KW - KW - Thailand DO - 10.3201/eid1707.101433 UR - https://wwwnc.cdc.gov/eid/article/17/7/10-1433_article ER - End of Reference