TY - JOUR AU - Aradaib, Imadeldin AU - Erickson, Bobbie AU - Elageb, Rehab AU - Khristova, Marina AU - Carroll, Serena AU - Elkhidir, Isam AU - Karsany, Mubarak AU - Karrar, AbdelRahim AU - Elbashir, Mustafa AU - Nichol, Stuart T1 - Rift Valley Fever, Sudan, 2007 and 2010 T2 - Emerging Infectious Disease journal PY - 2013 VL - 19 IS - 2 SP - 246 SN - 1080-6059 AB - To elucidate whether Rift Valley fever virus (RVFV) diversity in Sudan resulted from multiple introductions or from acquired changes over time from 1 introduction event, we generated complete genome sequences from RVFV strains detected during the 2007 and 2010 outbreaks. Phylogenetic analyses of small, medium, and large RNA segment sequences indicated several genetic RVFV variants were circulating in Sudan, which all grouped into Kenya-1 or Kenya-2 sublineages from the 2006–2008 eastern Africa epizootic. Bayesian analysis of sequence differences estimated that diversity among the 2007 and 2010 Sudan RVFV variants shared a most recent common ancestor circa 1996. The data suggest multiple introductions of RVFV into Sudan as part of sweeping epizootics from eastern Africa. The sequences indicate recent movement of RVFV and support the need for surveillance to recognize when and where RVFV circulates between epidemics, which can make data from prediction tools easier to interpret and preventive measures easier to direct toward high-risk areas. KW - Molecular characterization KW - disease outbreaks KW - Rift Valley fever KW - genomic analysis KW - phylogenetic relationship KW - Sudan KW - viruses KW - vector-borne infections DO - 10.3201/eid1902.120834 UR - https://wwwnc.cdc.gov/eid/article/19/2/12-0834_article ER - End of Reference