TY - JOUR AU - Fiebelkorn, Amy Parker AU - Lawler, Jacqueline AU - Curns, Aaron AU - Brandeburg, Christina AU - Wallace, Gregory T1 - Mumps Postexposure Prophylaxis with a Third Dose of Measles-Mumps-Rubella Vaccine, Orange County, New York, USA T2 - Emerging Infectious Disease journal PY - 2013 VL - 19 IS - 9 SP - 1411 SN - 1080-6059 AB - Although the measles-mumps-rubella (MMR) vaccine is not recommended for mumps postexposure prophylaxis (PEP), data on its effectiveness are limited. During the 2009–2010 mumps outbreak in the northeastern United States, we assessed effectiveness of PEP with a third dose of MMR vaccine among contacts in Orthodox Jewish households who were given a third dose within 5 days of mumps onset in the household’s index patient. We compared mumps attack rates between persons who received a third MMR dose during the first incubation period after onset in the index patient and 2-dose vaccinated persons who had not. Twenty-eight (11.7%) of 239 eligible household members received a third MMR dose as PEP. Mumps attack rates were 0% among third-dose recipients versus 5.2% among 2-dose recipients without PEP (p = 0.57). Although a third MMR dose administered as PEP did not have a significant effect, it may offer some benefits in specific outbreak contexts. KW - mumps KW - postexposure prophylaxis KW - third-dose MMR vaccine intervention KW - measles-mumps-rubella vaccine KW - viruses KW - New York KW - USA KW - United States DO - 10.3201/eid1909.130299 UR - https://wwwnc.cdc.gov/eid/article/19/9/13-0299_article ER - End of Reference