TY - JOUR AU - Middleton, Deborah AU - Pallister, Jackie AU - Klein, Reuben AU - Feng, Yan-Ru AU - Haining, Jessica AU - Arkinstall, Rachel AU - Frazer, Leah AU - Huang, Jin-An AU - Edwards, Nigel AU - Wareing, Mark AU - Elhay, Martin AU - Hashmi, Zia AU - Bingham, John AU - Yamada, Manabu AU - Johnson, Dayna AU - White, John AU - Foord, Adam AU - Heine, Hans AU - Marsh, Glenn AU - Broder, Christopher AU - Wang, Lin-Fa T1 - Hendra Virus Vaccine, a One Health Approach to Protecting Horse, Human, and Environmental Health T2 - Emerging Infectious Disease journal PY - 2014 VL - 20 IS - 3 SP - 379 SN - 1080-6059 AB - In recent years, the emergence of several highly pathogenic zoonotic diseases in humans has led to a renewed emphasis on the interconnectedness of human, animal, and environmental health, otherwise known as One Health. For example, Hendra virus (HeV), a zoonotic paramyxovirus, was discovered in 1994, and since then, infections have occurred in 7 humans, each of whom had a strong epidemiologic link to similarly affected horses. As a consequence of these outbreaks, eradication of bat populations was discussed, despite their crucial environmental roles in pollination and reduction of the insect population. We describe the development and evaluation of a vaccine for horses with the potential for breaking the chain of HeV transmission from bats to horses to humans, thereby protecting horse, human, and environmental health. The HeV vaccine for horses is a key example of a One Health approach to the control of human disease. Download MP3  Length: 1:13 KW - Hendra virus KW - HeV KW - vaccine KW - HeV vaccine KW - One-Health KW - G glycoprotein KW - zoonoses KW - viruses KW - zoonotic paramyxovirus KW - flying foxes KW - horses KW - humans KW - Pteropus bats KW - Australia KW - environment KW - vaccination KW - One Health DO - 10.3201/eid2003.131159 UR - https://wwwnc.cdc.gov/eid/article/20/3/13-1159_article ER - End of Reference