TY - JOUR AU - Jung, Kwonil AU - Wang, Qiuhong AU - Scheuer, Kelly AU - Lu, Zhongyan AU - Zhang, Yan AU - Saif, Linda T1 - Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs T2 - Emerging Infectious Disease journal PY - 2014 VL - 20 IS - 4 SP - 668 SN - 1080-6059 AB - To understand the progression of porcine epidemic diarrhea virus infection, we inoculated gnotobiotic pigs with a newly emerged US strain, PC21A, of the virus. At 24–48 hours postinoculation, the pigs exhibited severe diarrhea and vomiting, fecal shedding, viremia, and severe atrophic enteritis. These findings confirm that strain PC21A is highly enteropathogenic. KW - porcine epidemic diarrhea virus KW - porcine epidemic diarrhea, pathogenesis, outbreak, USA, gnotobiotic pigs, US strain, pigs, strain PC21A, viruses, enteropathogenic DO - 10.3201/eid2004.131685 UR - https://wwwnc.cdc.gov/eid/article/20/4/13-1685_article ER - End of Reference