TY - JOUR AU - Durand, Lizette AU - Glew, Patrick AU - Gross, Diane AU - Kasper, Matthew AU - Trock, Susan AU - Kim, Inkyu AU - Bresee, Joseph AU - Donis, Ruben AU - Uyeki, Timothy AU - Widdowson, Marc-Alain AU - Azziz-Baumgartner, Eduardo T1 - Timing of Influenza A(H5N1) in Poultry and Humans and Seasonal Influenza Activity Worldwide, 2004–2013 T2 - Emerging Infectious Disease journal PY - 2015 VL - 21 IS - 2 SP - 202 SN - 1080-6059 AB - Co-circulation of influenza A(H5N1) and seasonal influenza viruses among humans and animals could lead to co-infections, reassortment, and emergence of novel viruses with pandemic potential. We assessed the timing of subtype H5N1 outbreaks among poultry, human H5N1 cases, and human seasonal influenza in 8 countries that reported 97% of all human H5N1 cases and 90% of all poultry H5N1 outbreaks. In these countries, most outbreaks among poultry (7,001/11,331, 62%) and half of human cases (313/625, 50%) occurred during January–March. Human H5N1 cases occurred in 167 (45%) of 372 months during which outbreaks among poultry occurred, compared with 59 (10%) of 574 months that had no outbreaks among poultry. Human H5N1 cases also occurred in 59 (22%) of 267 months during seasonal influenza periods. To reduce risk for co-infection, surveillance and control of H5N1 should be enhanced during January–March, when H5N1 outbreaks typically occur and overlap with seasonal influenza virus circulation. KW - H5N1 KW - poultry KW - human KW - seasonal influenza KW - global KW - influenza KW - viruses KW - outbreaks KW - surveillance KW - biosafety DO - 10.3201/eid2102.140877 UR - https://wwwnc.cdc.gov/eid/article/21/2/14-0877_article ER - End of Reference