TY - JOUR
AU - Dumke, Roger
AU - Schnee, Christiane
AU - Pletz, Mathias
AU - Rupp, Jan
AU - Jacobs, Enno
AU - Sachse, Konrad
AU - Rohde, Gernot
AU - Group, CAPNETZ Study
T1 - Mycoplasma pneumoniae and Chlamydia spp. Infection in Community-Acquired Pneumonia, Germany, 2011–2012
T2 - Emerging Infectious Disease journal
PY - 2015
VL - 21
IS - 3
SP - 426
SN - 1080-6059
AB - Mycoplasma pneumoniae and Chlamydia spp., which are associated with community-acquired pneumonia (CAP), are difficult to propagate, and can cause clinically indistinguishable disease patterns. During 2011–2012, we used molecular methods to test adult patients in Germany with confirmed CAP for infection with these 2 pathogens. Overall, 12.3% (96/783) of samples were positive for M. pneumoniae and 3.9% (31/794) were positive for Chlamydia spp.; C. psittaci (2.1%) was detected more frequently than C. pneumoniae (1.4%). M. pneumoniae P1 type 1 predominated, and levels of macrolide resistance were low (3.1%). Quarterly rates of M. pneumoniae–positive samples ranged from 1.5% to 27.3%, showing a strong epidemic peak for these infections, but of Chlamydia spp. detection was consistent throughout the year. M. pneumoniae–positive patients were younger and more frequently female, had fewer co-occurring conditions, and experienced milder disease than did patients who tested negative. Clinicians should be aware of the epidemiology of these pathogens in CAP.
KW - community-acquired pneumonia
KW - CAP
KW - MLVA
KW - bacterial pneumonia
KW - outpatients
KW - molecular diagnostics
KW - Mycoplasma pneumoniae
KW - Chlamydia pneumoniae
KW - Chlamydia psittaci
KW - Chlamydia
KW - bacteria
KW - Germany
DO - 10.3201/eid2103.140927
UR - https://wwwnc.cdc.gov/eid/article/21/3/14-0927_article
ER - End of Reference