TY - JOUR AU - Nelson, Christina AU - Saha, Shubhayu AU - Kugeler, Kiersten AU - Delorey, Mark AU - Shankar, Manjunath AU - Hinckley, Alison AU - Mead, Paul T1 - Incidence of Clinician-Diagnosed Lyme Disease, United States, 2005–2010 T2 - Emerging Infectious Disease journal PY - 2015 VL - 21 IS - 9 SP - 1625 SN - 1080-6059 AB - National surveillance provides important information about Lyme disease (LD) but is subject to underreporting and variations in practice. Information is limited about the national epidemiology of LD from other sources. Retrospective analysis of a nationwide health insurance claims database identified patients from 2005–2010 with clinician-diagnosed LD using International Classification of Diseases, Ninth Revision, Clinical Modification, codes and antimicrobial drug prescriptions. Of 103,647,966 person-years, 985 inpatient admissions and 44,445 outpatient LD diagnoses were identified. Epidemiologic patterns were similar to US surveillance data overall. Outpatient incidence was highest among boys 5–9 years of age and persons of both sexes 60–64 years of age. On the basis of extrapolation to the US population and application of correction factors for coding, we estimate that annual incidence is 106.6 cases/100,000 persons and that ≈329,000 (95% credible interval 296,000–376,000) LD cases occur annually. LD is a major US public health problem that causes substantial use of health care resources. KW - Lyme disease KW - Borrelia burgdorferi KW - surveillance KW - United States KW - vector-borne infections KW - zoonoses KW - Ixodes KW - Emerging Infections Program KW - EIP DO - 10.3201/eid2109.150417 UR - https://wwwnc.cdc.gov/eid/article/21/9/15-0417_article ER - End of Reference