TY - JOUR AU - Huang, Bixing AU - Firth, Cadhla AU - Watterson, Daniel AU - Allcock, Richard AU - Colmant, Agathe M.G. AU - Hobson-Peters, Jody AU - Kirkland, Peter AU - Hewitson, Glen AU - McMahon, Jamie AU - Hall-Mendelin, Sonja AU - van den Hurk, Andrew AU - Warrilow, David T1 - Genetic Characterization of Archived Bunyaviruses and their Potential for Emergence in Australia T2 - Emerging Infectious Disease journal PY - 2016 VL - 22 IS - 5 SP - 833 SN - 1080-6059 AB - To better understand the diversity of bunyaviruses and their circulation in Australia, we sequenced 5 viruses (Gan Gan, Trubanaman, Kowanyama, Yacaaba, and Taggert) isolated and serologically identified 4 decades ago as members of the family Bunyaviridae. Gan Gan and Trubanaman viruses almost perfectly matched 2 recently isolated, purportedly novel viruses, Salt Ash and Murrumbidgee viruses, respectively. Kowanyama and Yacaaba viruses were identified as being related to members of a large clade containing pathogenic viruses. Taggert virus was confirmed as being a nairovirus; several viruses of this genus are pathogenic to humans. The genetic relationships and historical experimental infections in mice reveal the potential for these viruses to lead to disease emergence. KW - bunyavirus KW - emergence KW - arbovirus KW - sequencing KW - phylogenetics KW - viruses KW - Australia DO - 10.3201/eid2205.151566 UR - https://wwwnc.cdc.gov/eid/article/22/5/15-1566_article ER - End of Reference