TY - JOUR AU - Newitt, Sophie AU - MacGregor, Vanessa AU - Robbins, Vivienne AU - Bayliss, Laura AU - Chattaway, Marie Anne AU - Dallman, Tim AU - Ready, Derren AU - Aird, Heather AU - Puleston, Richard AU - Hawker, Jeremy T1 - Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014 T2 - Emerging Infectious Disease journal PY - 2016 VL - 22 IS - 7 SP - 1178 SN - 1080-6059 AB - Enteroinvasive Escherichia coli (EIEC) outbreaks are uncommon in Europe. In June 2014, two EIEC outbreaks occurred in Nottingham, UK, within 2 days; outbreak A was linked to a takeaway restaurant and outbreak B to a wedding party. We conducted 2 analytical studies: a case–control study for outbreak A and a cohort study for outbreak B. We tested microbiological and environmental samples, including by using whole-genome sequencing. For both outbreaks combined, we identified 157 probable case-patients; 27 were laboratory-confirmed as EIEC O96:H19–positive. Combined epidemiologic, microbiological, and environmental findings implicated lettuce as the vehicle of infection in outbreak A, but the source of the organism remained unknown. Whole-genome sequencing identified the same organism in cases from both outbreaks, but no epidemiologic link was confirmed. These outbreaks highlight that EIEC has the capacity to cause large and severe gastrointestinal disease outbreaks and should be considered as a potential pathogen in foodborne outbreaks in Europe. KW - Enteroinvasive KW - Escherichia KW - E. coli KW - EIEC KW - EIEC O96:H19 KW - bacteria KW - foodborne KW - gastrointestinal illness KW - Nottingham KW - England KW - United Kingdom KW - enteric infections KW - Food Safety DO - 10.3201/eid2207.152080 UR - https://wwwnc.cdc.gov/eid/article/22/7/15-2080_article ER - End of Reference