TY - JOUR
AU - Haviari, Skerdi
AU - Cassier, Pierre
AU - Dananché, Cédric
AU - Hulin, Monique
AU - Dauwalder, Olivier
AU - Rouvière, Olivier
AU - Bertrand, Xavier
AU - Perraud, Michel
AU - Bénet, Thomas
AU - Vanhems, Philippe
T1 - Outbreak of Achromobacter xylosoxidans and Ochrobactrum anthropi Infections after Prostate Biopsies, France, 2014
T2 - Emerging Infectious Disease journal
PY - 2016
VL - 22
IS - 8
SP - 1412
SN - 1080-6059
AB - We report an outbreak of healthcare-associated prostatitis involving rare environmental pathogens in immunocompetent patients undergoing transrectal prostate biopsies at Hôpital Édouard Herriot (Lyon, France) during August 13–October 10, 2014. Despite a fluoroquinolone-based prophylaxis, 5 patients were infected with Achromobacter xylosoxidans and 3 with Ochrobactrum anthropi, which has not been reported as pathogenic in nonimmunocompromised persons. All patients recovered fully. Analysis of the outbreak included case investigation, case–control study, biopsy procedure review, microbiologic testing of environmental and clinical samples, and retrospective review of hospital records for 4 years before the outbreak. The cases resulted from asepsis errors during preparation of materials for the biopsies. A low-level outbreak involving environmental bacteria was likely present for years, masked by antimicrobial drug prophylaxis and a low number of cases. Healthcare personnel should promptly report unusual pathogens in immunocompetent patients to infection control units, and guidelines should explicitly mention asepsis during materials preparation.
KW - Achromobacter xylosoxidans
KW - Achromobacter denitrificans
KW - Ochrobactrum anthropi
KW - disease outbreaks
KW - prostate
KW - prostatitis
KW - prostatic diseases
KW - diagnostic techniques
KW - clinical laboratory techniques
KW - surgical
KW - biopsy
KW - gram-negative bacteria
KW - bacteria
KW - France
DO - 10.3201/eid2208.151423
UR - https://wwwnc.cdc.gov/eid/article/22/8/15-1423_article
ER - End of Reference