TY - JOUR AU - Bower, Hilary AU - Johnson, Sembia AU - Bangura, Mohamed AU - Kamara, Alie Joshua AU - Kamara, Osman AU - Mansaray, Saidu AU - Sesay, Daniel AU - Turay, Cecilia AU - Checchi, Francesco AU - Glynn, Judith T1 - Exposure-Specific and Age-Specific Attack Rates for Ebola Virus Disease in Ebola-Affected Households, Sierra Leone T2 - Emerging Infectious Disease journal PY - 2016 VL - 22 IS - 8 SP - 1403 SN - 1080-6059 AB - Using histories of household members of Ebola virus disease (EVD) survivors in Sierra Leone, we calculated risk of EVD by age and exposure level, adjusting for confounding and clustering, and estimated relative risks. Of 937 household members in 94 households, 448 (48%) had had EVD. Highly correlated with exposure, EVD risk ranged from 83% for touching a corpse to 8% for minimal contact and varied by age group: 43% for children <2 years of age; 30% for those 5–14 years of age; and >60% for adults >30 years of age. Compared with risk for persons 20–29 years of age, exposure-adjusted relative risks were lower for those 5–9 (0.70), 10–14 (0.64), and 15–19 (0.71) years of age but not for children <2 (0.92) or 2–4 (0.97) years of age. Lower risk for 5–19-year-olds, after adjustment for exposure, suggests decreased susceptibility in this group. KW - Ebola KW - Ebola virus KW - Ebola virus disease KW - viruses KW - attack rates KW - risk factors KW - exposures KW - transmission KW - survivors KW - households KW - cohort study KW - Sierra Leone KW - infectious disease transmission DO - 10.3201/eid2208.160163 UR - https://wwwnc.cdc.gov/eid/article/22/8/16-0163_article ER - End of Reference